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CHARMed collaboration creates a potent therapy candidate for fatal prion diseases

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Drug development is typically slow: The pipeline from basic research discoveries that provide the basis for a new drug to clinical trials and then production of a widely available medicine can take decades. But decades can feel impossibly far off to someone who currently has a fatal disease. Broad Institute of MIT and Harvard Senior Group Leader Sonia Vallabh is acutely aware of that race against time, because the topic of her research is a neurodegenerative and ultimately fatal disease — fatal familial insomnia, a type of prion disease — that she will almost certainly develop as she ages. 

Vallabh and her husband, Eric Minikel, switched careers and became researchers after they learned that Vallabh carries a disease-causing version of the prion protein gene and that there is no effective therapy for fatal prion diseases. The two now run a lab at the Broad Institute, where they are working to develop drugs that can prevent and treat these diseases, and their deadline for success is not based on grant cycles or academic expectations but on the ticking time bomb in Vallabh’s genetic code.

That is why Vallabh was excited to discover, when she entered into a collaboration with Whitehead Institute for Biomedical Research member Jonathan Weissman, that Weissman’s group likes to work at full throttle. In less than two years, Weissman, Vallabh, and their collaborators have developed a set of molecular tools called CHARMs that can turn off disease-causing genes such as the prion protein gene — as well as, potentially, genes coding for many other proteins implicated in neurodegenerative and other diseases — and they are refining those tools to be good candidates for use in human patients. Although the tools still have many hurdles to pass before the researchers will know if they work as therapeutics, the team is encouraged by the speed with which they have developed the technology thus far.

“The spirit of the collaboration since the beginning has been that there was no waiting on formality,” Vallabh says. “As soon as we realized our mutual excitement to do this, everything was off to the races.”

Co-corresponding authors Weissman and Vallabh and co-first authors Edwin Neumann, a graduate student in Weissman’s lab, and Tessa Bertozzi, a postdoc in Weissman’s lab, describe CHARM — which stands for Coupled Histone tail for Autoinhibition Release of Methyltransferase — in a paper published today in the journal Science .

“With the Whitehead and Broad Institutes right next door to each other, I don’t think there’s any better place than this for a group of motivated people to move quickly and flexibly in the pursuit of academic science and medical technology,” says Weissman, who is also a professor of biology at MIT and a Howard Hughes Medical Institute Investigator. “CHARMs are an elegant solution to the problem of silencing disease genes, and they have the potential to have an important position in the future of genetic medicines.”

To treat a genetic disease, target the gene

Prion disease, which leads to swift neurodegeneration and death, is caused by the presence of misshapen versions of the prion protein. These cause a cascade effect in the brain: the faulty prion proteins deform other proteins, and together these proteins not only stop functioning properly but also form toxic aggregates that kill neurons. The most famous type of prion disease, known colloquially as mad cow disease, is infectious, but other forms of prion disease can occur spontaneously or be caused by faulty prion protein genes.

Most conventional drugs work by targeting a protein. CHARMs, however, work further upstream, turning off the gene that codes for the faulty protein so that the protein never gets made in the first place. CHARMs do this by epigenetic editing, in which a chemical tag gets added to DNA in order to turn off or silence a target gene. Unlike gene editing, epigenetic editing does not modify the underlying DNA — the gene itself remains intact. However, like gene editing, epigenetic editing is stable, meaning that a gene switched off by CHARM should remain off. This would mean patients would only have to take CHARM once, as opposed to protein-targeting medications that must be taken regularly as the cells’ protein levels replenish.

Research in animals suggests that the prion protein isn’t necessary in a healthy adult, and that in cases of disease, removing the protein improves or even eliminates disease symptoms. In a person who hasn’t yet developed symptoms, removing the protein should prevent disease altogether. In other words, epigenetic editing could be an effective approach for treating genetic diseases such as inherited prion diseases. The challenge is creating a new type of therapy.

Fortunately, the team had a good template for CHARM: a research tool called CRISPRoff that Weissman’s group previously developed for silencing genes. CRISPRoff uses building blocks from CRISPR gene editing technology, including the guide protein Cas9 that directs the tool to the target gene. CRISPRoff silences the targeted gene by adding methyl groups, chemical tags that prevent the gene from being transcribed, or read into RNA, and so from being expressed as protein. When the researchers tested CRISPRoff’s ability to silence the prion protein gene, they found that it was effective and stable.

Several of its properties, though, prevented CRISPRoff from being a good candidate for a therapy. The researchers’ goal was to create a tool based on CRISPRoff that was just as potent but also safe for use in humans, small enough to deliver to the brain, and designed to minimize the risk of silencing the wrong genes or causing side effects.

From research tool to drug candidate

Led by Neumann and Bertozzi, the researchers began engineering and applying their new epigenome editor. The first problem that they had to tackle was size, because the editor needs to be small enough to be packaged and delivered to specific cells in the body. Delivering genes into the human brain is challenging; many clinical trials have used adeno-associated viruses (AAVs) as gene-delivery vehicles, but these are small and can only contain a small amount of genetic code. CRISPRoff is way too big; the code for Cas9 alone takes up most of the available space.

The Weissman lab researchers decided to replace Cas9 with a much smaller zinc finger protein (ZFP). Like Cas9, ZFPs can serve as guide proteins to direct the tool to a target site in DNA. ZFPs are also common in human cells, meaning they are less likely to trigger an immune response against themselves than the bacterial Cas9.

Next, the researchers had to design the part of the tool that would silence the prion protein gene. At first, they used part of a methyltransferase, a molecule that adds methyl groups to DNA, called DNMT3A. However, in the particular configuration needed for the tool, the molecule was toxic to the cell. The researchers focused on a different solution: Instead of delivering outside DNMT3A as part of the therapy, the tool is able to recruit the cell’s own DNMT3A to the prion protein gene. This freed up precious space inside of the AAV vector and prevented toxicity.

The researchers also needed to activate DNMT3A. In the cell, DNMT3A is usually inactive until it interacts with certain partner molecules. This default inactivity prevents accidental methylation of genes that need to remain turned on. Neumann came up with an ingenious way around this by combining sections of DNMT3A’s partner molecules and connecting these to ZFPs that bring them to the prion protein gene. When the cell’s DNMT3A comes across this combination of parts, it activates, silencing the gene.

“From the perspectives of both toxicity and size, it made sense to recruit the machinery that the cell already has; it was a much simpler, more elegant solution,” Neumann says. “Cells are already using methyltransferases all of the time, and we’re essentially just tricking them into turning off a gene that they would normally leave turned on.”

Testing in mice showed that ZFP-guided CHARMs could eliminate more than 80 percent of the prion protein in the brain, while previous research has shown that as little as 21 percent elimination can improve symptoms.

Once the researchers knew that they had a potent gene silencer, they turned to the problem of off-target effects. The genetic code for a CHARM that gets delivered to a cell will keep producing copies of the CHARM indefinitely. However, after the prion protein gene is switched off, there is no benefit to this, only more time for side effects to develop, so they tweaked the tool so that after it turns off the prion protein gene, it then turns itself off.

Meanwhile, a complementary project from Broad Institute scientist and collaborator Benjamin Deverman’s lab, focused on brain-wide gene delivery and published in Science on May 17, has brought the CHARM technology one step closer to being ready for clinical trials. Although naturally occurring types of AAV have been used for gene therapy in humans before, they do not enter the adult brain efficiently, making it impossible to treat a whole-brain disease like prion disease. Tackling the delivery problem, Deverman’s group has designed an AAV vector that can get into the brain more efficiently by leveraging a pathway that naturally shuttles iron into the brain. Engineered vectors like this one make a therapy like CHARM one step closer to reality.

Thanks to these creative solutions, the researchers now have a highly effective epigenetic editor that is small enough to deliver to the brain, and that appears in cell culture and animal testing to have low toxicity and limited off-target effects.

“It’s been a privilege to be part of this; it’s pretty rare to go from basic research to therapeutic application in such a short amount of time,” Bertozzi says. “I think the key was forming a collaboration that took advantage of the Weissman lab’s tool-building experience, the Vallabh and Minikel lab’s deep knowledge of the disease, and the Deverman lab’s expertise in gene delivery.”

Looking ahead

With the major elements of the CHARM technology solved, the team is now fine-tuning their tool to make it more effective, safer, and easier to produce at scale, as will be necessary for clinical trials. They have already made the tool modular, so that its various pieces can be swapped out and future CHARMs won’t have to be programmed from scratch. CHARMs are also currently being tested as therapeutics in mice. 

The path from basic research to clinical trials is a long and winding one, and the researchers know that CHARMs still have a way to go before they might become a viable medical option for people with prion diseases, including Vallabh, or other diseases with similar genetic components. However, with a strong therapy design and promising laboratory results in hand, the researchers have good reason to be hopeful. They continue to work at full throttle, intent on developing their technology so that it can save patients’ lives not someday, but as soon as possible.

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• How Americans View National, Local and Personal Energy Choices

Most Americans want more renewable energy, but support has dipped. Interest in electric vehicles has also declined

Table of contents.

• 1. Views on energy development in the U.S.
• 2. Americans’ views on local wind and solar power development
• 3. Americans’ perceptions of solar power in their own lives
• Acknowledgments
• The American Trends Panel survey methodology
• Appendix: Detailed charts and tables

Pew Research Center conducted this study to understand Americans’ views of energy issues. For this analysis, we surveyed 8,638 U.S. adults from May 13 to 19, 2024.

Everyone who took part in the survey is a member of the Center’s American Trends Panel (ATP), an online survey panel that is recruited through national, random sampling of residential addresses. This way, nearly all U.S. adults have a chance of selection. The survey is weighted to be representative of the U.S. adult population by gender, race, ethnicity, partisan affiliation, education and other categories. Read more about the ATP’s methodology .

Here are the questions used for this report , along with responses, and its Methodology .

The planet’s continued streak of record heat has spurred calls for action by scientists and global leaders . Meanwhile, in the United States, energy development policy is being hotly debated on the national and local levels this election year. How do Americans feel about U.S. energy policy options, and what steps are they willing to take in their own lives to reduce carbon emissions? A new Pew Research Center survey takes a look.

Among the major findings:

There’s been a decline in the breadth of support for wind and solar power. The shares who favor expanding solar and wind power farms are down 12 percentage points and 11 points, respectively, since 2020, driven by sharp drops in support among Republicans.

Interest in buying an electric vehicle (EV) is lower than a year ago. Today, 29% of Americans say they would consider an EV for their next purchase, down from 38% in 2023.

Still, a majority of Americans (63%) support the goal of the U.S. taking steps to become carbon neutral by 2050. When asked which is the greater priority, far more Americans continue to say the country should focus on developing renewable energy than fossil fuel sources (65% vs. 34%).

The survey, conducted May 13-19 among 8,638 U.S. adults, finds a fairly modest share of U.S. adults (25%) say it’s extremely or very important to them personally to limit their own “carbon footprint.” Far more give this middling or low priority.

These findings illustrate how large shares of Americans back more renewable energy that would decrease overall carbon emissions. Still, this general orientation does not necessarily translate into strong commitment to reducing personal carbon emissions or interest in buying an EV.

Jump to read more on: Trends in views of energy development in the U.S. | Views on wind and solar development at the local level | Perceptions of solar power in people’s own lives

What’s behind declines in support for wind and solar?

Declines in public support for renewable energy have been driven by Republicans and Republican-leaning independents, whose support started to fall sharply after President Joe Biden took office in early 2020.

• 64% of Republicans say they favor more solar panel farms, down from 84% in 2020.
• 56% of Republicans say they favor more wind turbine farms, a 19-point drop from 2020.

Over this same time period, views among Democrats and Democratic leaners on these measures are little changed, with large majorities continuing to support more wind and solar development.

In some cases, gaps between Republicans and Democrats over energy policy now approach the very wide partisan divides seen over the importance of climate change .

In May 2020, Democrats were 26 points more likely than Republicans to say the country’s priority should be developing renewable energy (91% vs. 65%). Four years later, that gap has ballooned to 49 points, due almost entirely to changing views among Republicans – 61% of whom now say developing fossil fuels like oil, coal and natural gas should be the more important priority.

Jump to more details on partisan differences in views of U.S. energy development.

But changes in attitudes about policies that would reduce carbon emissions are not solely the result of more negative views among Republicans. For instance, the share of Democrats who say they are very or somewhat likely to consider an EV for their next car purchase has declined from 56% to 45% in the last year. And the share of Democrats who call climate change a very big problem for the U.S. has declined from 71% in 2021 to 58% today.

Views within each party

Among Republicans, age matters. Younger Republicans express much more support for renewable energy than do older Republicans. For instance, 67% of Republicans ages 18 to 29 say the country should give priority to wind, solar and hydrogen development. The oldest Republicans (ages 65 and older) take the opposite view: 76% give priority to developing oil, coal and natural gas.

By and large, Democrats are more united in their views on energy. Democrats across age groups broadly support steps that would lower carbon emissions and prioritize renewable sources. But differences emerge over the degree with which to break from fossil fuels: 45% of Democrats say the country should phase out the use of oil, coal and natural gas completely, compared with 53% who say that fossil fuels should remain part of the mix along with renewable sources.

Differences within the two major parties are explored in more detail here .

Views on increasing electric vehicles in the U.S.

Amid a major policy push at the federal level for electric vehicles, Americans are unenthusiastic about steps that would phase out gas-powered vehicles.

In March of this year, the Biden administration announced a rule aimed at dramatically expanding EV sales . Overall, 58% of Americans say they oppose these rules that would make EVs at least half of all new cars and trucks sold in the U.S. by 2032. Republicans overwhelmingly oppose this policy (83%). Among Democrats, 64% support these rules to expand EV sales, while 35% say they oppose them.

Americans bought EVs in record numbers last year, but the growth rate is slowing, and interest in EVs has declined. In the current survey, 29% of Americans say they are very or somewhat likely to consider an electric vehicle the next time they purchase a car. Last year, 38% expressed this level of interest in an EV purchase.

Related: About 3 in 10 Americans would seriously consider buying an electric vehicle and the distribution of EV charging stations in the U.S.

Americans’ views on limiting their own ‘carbon footprint’

Discussions about reducing carbon emissions often include the everyday actions people can take to reduce the amount of energy they use . One-in-four Americans say it is extremely or very important to them personally to limit their own “carbon footprint.” Larger shares say this is either somewhat (42%) or not too or not at all (32%) important to them.

Even among Democrats – who express broad support for renewable energy – only 39% say reducing their own carbon footprint is extremely or very important to them personally.

These findings align with a previous Center survey that shows a modest share of Americans (23%) expect to make major sacrifices in their own life because of climate change.

Simply put, the shares of Americans who place the highest priority on limiting their own carbon emissions or expect to make big changes to the way they live because of climate change remain relatively small.

Those who place a high priority on reducing their own carbon footprint – or expect major direct impacts from climate change – are far more likely than other Americans to back aggressive steps to reduce carbon emissions.

For instance, 70% of those who place high importance on reducing their own carbon footprint support rules to dramatically boost EV sales in the U.S. by 2032. Much smaller shares of those who say reducing their carbon footprint is somewhat (43%) or not too or not at all (14%) important support this policy.

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June 26, 2024

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New research shows that improving mobile internet service can reduce digital inequality

by Georgia Institute of Technology

New research shows removing data caps to cell phone usage may not only reduce digital inequality but might increase education data consumption by disadvantaged populations.

More than 90% of the U.S. population has internet access. However, many households , particularly those of low socioeconomic status, are "smartphone-dependent," meaning they rely purely on their smartphone for internet access. As a result, their connection may be unstable or slow, and they may be constrained by data caps that limit how much they can use the internet.

This puts them at a disadvantage compared to households with internet access through smartphones and other broadband connections at home and work, perpetuating digital inequality between disadvantaged and advantaged households.

The smartphone dependence of many disadvantaged households begs the question: If mobile internet service was better—e.g., if it was faster, more reliable, and/or didn't come with data constraints—could that reduce digital inequality and level the playing field? Researchers from the Georgia Tech Scheller College of Business and Southern Methodist University Cox School of Business studied this question and found the answer is "yes."

The research paper is forthcoming in Management Science and is available on the SSRN site.

Karthik Kannan, assistant professor of IT and Operations Management at the Cox School of Business and Georgia Tech Ph.D. graduate, led the project. "I was interested in the effect of data caps. For example, when you have 10GB of data per month and use more, you are charged extra, or your connection is throttled," said Kannan.

"So, I partnered with a large telecommunications provider to study what happens when their subscribers switched from capped to unlimited data plans. I was particularly interested in differences between high-income and low-income households."

Kannan, along with Eric Overby, Catherine and Edwin Wahlen Professor of Information Technology Management, and Sri Narasimhan, Gregory J. Owens Professor of Information Technology Management, at the Scheller College of Business, found that while all households increased their data use after switching to an unlimited plan, the increase was significantly larger for families of low socioeconomic status .

"That was our initial finding: that improving mobile internet service by removing the data cap had disproportionately large benefits for disadvantaged households," said Overby. "But that didn't mean much in and of itself. If those households weren't using the additional data for 'enriching' purposes like accessing educational, health care , or career-related data, the additional data consumption wouldn't translate into positive social benefits.

"Indeed, years of research on digital inequality have consistently shown a 'usage gap' in which advantaged households take fuller advantage of internet access improvements than disadvantaged households. The result is that internet improvements often exacerbate inequality. So, we dug deeper."

Specifically, the researchers leveraged the telecommunication provider's data categorization system to study changes in the consumption of educational data. They found that disadvantaged households experienced disproportionate increases in education data consumption (as well as in overall data consumption) after switching to unlimited mobile data.

Although advantaged households increased their education data consumption by approximately 15MB (or about three digital textbooks) per month after switching to unlimited data, disadvantaged households increased their education data consumption by approximately 24MB (or about five digital textbooks) per month.

"We can't be sure that these disproportionate increases in education data consumption will help disadvantaged households narrow gaps in educational outcomes. However, this is clearly a step in the right direction," said Kannan.

The research is directly relevant to the Federal Communications Commission's 2023 inquiry into the effects of data caps on disadvantaged households. Narasimhan explains, "Let's say that based on their inquiry, the FCC decides to limit the use of data caps. A logical question is: will that do any good? In other words, will disadvantaged households take advantage of their improved mobile internet service in a way that can reduce digital inequality? Prior to our research, we didn't really know. But based on our research, the answer is yes."

Journal information: Management Science

Provided by Georgia Institute of Technology

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Home » 300+ Interesting Research Topics

300+ Interesting Research Topics

Research is a vital component of any academic pursuit, and the process of choosing an interesting research topic can be both exciting and daunting. With countless subjects and themes to explore, it can be challenging to narrow down your focus and find a topic that resonates with you. However, the right research topic can inspire you, engage your curiosity, and drive you to discover new insights and knowledge. In this post, we’ll explore some interesting research topics across a variety of disciplines, providing you with a starting point for your next academic project.

Interesting Research Topics

Some Interesting Research Topics are as follows:

• The impact of mindfulness meditation on creativity and innovative problem-solving abilities
• The relationship between social media use and political activism among young adults
• The effectiveness of virtual reality therapy for treating specific phobias
• The role of nutrition in preventing and managing anxiety disorders
• The impact of cultural factors on perceptions and experiences of workplace harassment and discrimination
• The relationship between personality traits and successful entrepreneurship
• The effects of outdoor education programs on academic achievement and environmental attitudes in middle school students
• The role of physical activity in improving cognitive function and memory in older adults
• The impact of cultural factors on perceptions and experiences of aging and technology use
• The relationship between social support and mental health outcomes in individuals with chronic illnesses
• The effects of cognitive-behavioral therapy for eating disorders in males
• The role of nutrition in preventing and managing osteoporosis in postmenopausal women
• The impact of cultural factors on attitudes towards organ donation and transplantation
• The relationship between sleep and athletic performance in professional athletes
• The effects of mindfulness-based interventions on reducing implicit biases and promoting workplace diversity and inclusion
• The role of physical activity in reducing symptoms of postpartum depression in new mothers
• The impact of cultural factors on perceptions and experiences of maternal mental health in diverse communities
• The relationship between childhood socioeconomic status and adult health outcomes
• The effects of cognitive-behavioral therapy for hoarding disorder
• The role of nutrition in preventing and managing chronic pain conditions, such as fibromyalgia.
• The effects of social media use on political polarization and civic engagement
• The impact of mindfulness on reducing workplace stress and burnout
• The relationship between personality and job performance in different work settings
• The effectiveness of dialectical behavior therapy for individuals with bipolar disorder
• The role of exercise in improving mental health outcomes in college students
• The effects of technology on social interactions and relationship quality in romantic relationships
• The impact of cultural factors on mental health treatment-seeking behavior in immigrant populations
• The relationship between parental attachment and emotional regulation in adolescence
• The effectiveness of cognitive-behavioral therapy for post-traumatic stress disorder (PTSD) in military veterans
• The role of nutrition in preventing and managing cardiovascular disease
• The effects of mindfulness on reducing implicit biases and promoting diversity and inclusion
• The impact of cultural values on decision-making in the context of environmental sustainability
• The relationship between sleep and academic performance in high school students
• The effectiveness of acceptance and commitment therapy for individuals with substance use disorders
• The role of physical activity in reducing symptoms of depression in older adults
• The impact of cultural factors on coping strategies and resilience in disaster recovery
• The relationship between parental warmth and child social competence in early childhood
• The effects of cognitive-behavioral therapy for depression in cancer patients
• The role of nutrition in preventing and managing autoimmune skin diseases, such as psoriasis
• The effects of virtual reality exposure therapy on treating social anxiety disorder
• The impact of gender diversity in leadership positions on organizational performance and innovation
• The relationship between social support and mental health outcomes in college students
• The effects of art therapy on reducing symptoms of PTSD in military veterans
• The role of physical activity in reducing symptoms of anxiety in pregnant women
• The impact of cultural factors on perceptions and experiences of aging and age-related health issues
• The relationship between childhood trauma and academic achievement in adolescence
• The effects of cognitive-behavioral therapy for borderline personality disorder
• The role of nutrition in preventing and managing eye diseases, such as macular degeneration
• The effectiveness of mindfulness-based stress reduction for individuals with chronic pain
• The impact of cultural factors on attitudes towards mental health treatment in African American communities
• The relationship between parental monitoring and adolescent substance use
• The effects of equine therapy on reducing symptoms of ADHD in children
• The role of physical activity in improving quality of life in individuals with Parkinson’s disease
• The impact of cultural factors on leadership style and effectiveness in multinational corporations
• The relationship between social media use and self-esteem in young adults
• The effects of cognitive-behavioral therapy for insomnia in older adults
• The role of nutrition in preventing and managing gastrointestinal disorders, such as irritable bowel syndrome
• The impact of cultural factors on perceptions and experiences of mental health treatment in LGBTQ+ communities
• The relationship between parental discipline and child behavior problems in preschoolers
• The effects of music therapy on reducing symptoms of depression in older adults with dementia
• The role of physical activity in reducing symptoms of depression in individuals with multiple sclerosis
• The impact of cultural factors on perceptions and experiences of disability and accessibility
• The relationship between childhood adversity and adult physical health outcomes
• The effects of cognitive-behavioral therapy for anxiety in individuals with autism spectrum disorder
• The role of nutrition in preventing and managing liver diseases, such as hepatitis and cirrhosis
• The impact of cultural factors on perceptions and experiences of health care and health care utilization
• The effects of social media on mental health in adolescents
• The impact of mindfulness meditation on stress reduction in the workplace
• The relationship between exercise and cognitive function in aging adults
• The role of nutrition in the prevention and management of chronic diseases
• The effectiveness of virtual reality therapy for anxiety disorders
• The effects of sleep deprivation on academic performance in college students
• The relationship between personality traits and job satisfaction in the workplace
• The impact of technology on interpersonal communication and relationships
• The effectiveness of cognitive behavioral therapy for depression
• The effects of music therapy on pain management in hospitalized patients
• The relationship between parenting styles and child development outcomes
• The role of exercise in the prevention and management of Type 2 diabetes
• The effects of gaming on cognitive function and decision making skills
• The impact of mindfulness on academic performance in college students
• The relationship between self-esteem and academic achievement in adolescents
• The effectiveness of online education compared to traditional classroom instruction
• The effects of physical activity on mental health in adults
• The impact of social support on psychological well-being in cancer patients
• The relationship between personality and substance abuse disorders
• The role of early childhood education in later academic achievement
• The effects of nature exposure on stress reduction and mental health
• The impact of art therapy on emotional regulation in children with autism spectrum disorder
• The relationship between body image and eating disorders
• The effectiveness of cognitive rehabilitation for individuals with traumatic brain injury
• The effects of exercise on sleep quality and duration in older adults
• The impact of cultural diversity on team performance in the workplace
• The relationship between mindfulness and substance abuse recovery
• The role of exercise in the prevention and management of cardiovascular disease
• The effects of mindfulness on chronic pain management
• The impact of technology on academic integrity in higher education
• The relationship between work-life balance and job satisfaction in healthcare professionals
• The effectiveness of cognitive-behavioral therapy for anxiety disorders in children
• The effects of outdoor play on physical activity and social skills in children
• The impact of group therapy on social anxiety disorder
• The relationship between resilience and mental health outcomes in individuals with chronic illness
• The role of social support in promoting healthy behaviors in older adults
• The effects of physical activity on executive functioning in children with ADHD
• The impact of family therapy on child behavior problems
• The relationship between emotional intelligence and leadership effectiveness
• The effectiveness of cognitive rehabilitation for individuals with schizophrenia
• The effects of art therapy on social skills and emotional regulation in children with ADHD
• The impact of mindfulness on academic performance in high school students
• The relationship between resilience and posttraumatic growth in survivors of sexual assault
• The role of exercise in the prevention and management of osteoporosis
• The effects of mindfulness on emotional regulation in individuals with borderline personality disorder
• The impact of social media on body image and self-esteem in adolescents
• The relationship between personality and academic achievement in college students
• The effectiveness of cognitive-behavioral therapy for postpartum depression
• The effects of aerobic exercise on cognitive function and depression in older adults
• The impact of group therapy on social skills and self-esteem in individuals with social anxiety disorder.
• The effects of social media on political polarization and civic engagement
• The impact of mindfulness-based interventions on substance use disorder recovery
• The relationship between emotional intelligence and workplace productivity
• The role of physical activity in preventing and managing chronic pain
• The effects of music therapy on speech and language development in children with developmental disorders
• The impact of organizational culture on employee job satisfaction and turnover
• The relationship between childhood trauma and adult mental health outcomes
• The effectiveness of acceptance and commitment therapy for anxiety disorders
• The effects of early childhood bilingual education on language development and academic achievement
• The role of nutrition in the prevention and treatment of depression
• The impact of virtual reality exposure therapy on phobia treatment outcomes
• The relationship between social support and mental health in LGBTQ+ individuals
• The effects of exercise on mood and cognitive function in individuals with major depressive disorder
• The role of mindfulness in reducing symptoms of burnout in healthcare professionals
• The effectiveness of trauma-focused cognitive behavioral therapy for posttraumatic stress disorder
• The effects of video game addiction on social skills and academic performance in adolescents
• The impact of peer mentoring on academic achievement and self-esteem in at-risk youth
• The relationship between personality and creativity in the workplace
• The role of nutrition in promoting healthy aging and cognitive function in older adults
• The effects of animal-assisted therapy on mental health in adults with chronic illness
• The impact of work-family conflict on employee well-being and job performance
• The relationship between childhood bullying and adult mental health outcomes
• The effectiveness of cognitive-behavioral therapy for insomnia
• The effects of mindfulness-based stress reduction on chronic pain management in older adults
• The role of physical activity in preventing and managing anxiety disorders
• The impact of cultural competence training on healthcare provider-patient communication and health outcomes
• The relationship between personality and leadership styles in the workplace
• The effects of play therapy on social skills and emotional regulation in children with autism spectrum disorder
• The role of nutrition in reducing the risk of cognitive decline in individuals with Alzheimer’s disease
• The impact of workplace diversity on team creativity and innovation
• The relationship between social media use and sleep quality in adolescents
• The effectiveness of dialectical behavior therapy for borderline personality disorder
• The effects of exercise on cognitive function and academic performance in children
• The role of mindfulness in reducing stress and promoting well-being in college students
• The impact of group therapy on social skills and emotional regulation in individuals with eating disorders
• The relationship between personality and job performance in creative fields
• The effects of exposure to green spaces on mental health in urban populations
• The role of nutrition in the prevention and management of autoimmune disorders
• The impact of mindfulness-based interventions on reducing anxiety and depression in cancer patients
• The relationship between emotional intelligence and job satisfaction in healthcare professionals
• The effectiveness of cognitive-behavioral therapy for obsessive-compulsive disorder
• The effects of mindfulness on pain management in individuals with chronic pain
• The role of physical activity in promoting healthy aging and preventing age-related diseases
• The impact of parental involvement on academic achievement in children from low-income families
• The relationship between personality and online behavior in social media platforms
• The effects of expressive writing on mental health outcomes in individuals with posttraumatic stress disorder
• The role of nutrition in reducing inflammation and promoting cardiovascular health
• The impact of diversity training on reducing implicit biases in the workplace
• The relationship between social media use and body dissatisfaction in women
• The effects of technology on interpersonal communication in romantic relationships
• The effects of early childhood bilingualism on cognitive development
• The effects of social media use on political engagement and participation
• The effects of social media use on body image dissatisfaction and eating disorders in young adults
• The impact of workplace wellness programs on employee health and productivity
• The relationship between personality and entrepreneurial success
• The effectiveness of group therapy for individuals with borderline personality disorder
• The role of sleep in athletic performance and recovery
• The effects of mindfulness on reducing racial biases and promoting social justice
• The impact of cultural values on medical decision-making and healthcare outcomes
• The relationship between childhood trauma and adult attachment styles in romantic relationships
• The effectiveness of cognitive-behavioral therapy for anxiety disorders in children and adolescents
• The role of nutrition in preventing and managing cognitive decline in older adults
• The effects of virtual reality exposure therapy on treating obsessive-compulsive disorder
• The impact of job satisfaction on employee turnover and organizational performance
• The relationship between cultural differences and negotiation outcomes in cross-border mergers and acquisitions
• The effects of pet therapy on reducing symptoms of depression and anxiety in nursing home residents
• The role of physical activity in improving sleep quality and quantity
• The impact of cultural values on perceptions of mental health and attitudes towards seeking help
• The relationship between parental involvement and academic achievement in elementary school students
• The effectiveness of acceptance and commitment therapy for individuals with chronic pain
• The role of nutrition in reducing the risk of cognitive disorders, such as Alzheimer’s disease
• The effects of cognitive-behavioral therapy for insomnia in adults
• The impact of gender diversity on board of directors on firm performance and innovation
• The effects of virtual reality exposure therapy on treating specific phobias
• The role of physical activity in preventing and managing chronic pain conditions
• The impact of cross-cultural communication skills on expatriate adjustment and success
• The relationship between childhood trauma and addiction in adulthood
• The effects of art therapy on reducing symptoms of depression and anxiety in cancer patients
• The role of nutrition in promoting healthy aging and longevity
• The effectiveness of cognitive-behavioral therapy for eating disorders in adults
• The impact of cultural values on decision-making in the workplace
• The relationship between socioeconomic status and mental health outcomes in children and adolescents
• The effects of virtual reality exposure therapy on treating eating disorders
• The impact of cultural intelligence on intercultural communication competence
• The relationship between childhood trauma and personality disorders in adulthood
• The effects of music therapy on reducing symptoms of anxiety and depression in individuals with autism spectrum disorder
• The role of nutrition in preventing and managing metabolic disorders, such as diabetes and obesity
• The impact of leadership styles on employee motivation and job satisfaction
• The relationship between cultural differences and expatriate adjustment in multinational corporations
• The effects of cognitive-behavioral therapy for insomnia in children and adolescents
• The role of physical activity in reducing symptoms of ADHD in children
• The impact of cultural values on perceptions of mental health stigma
• The relationship between parental stress and child development outcomes
• The effects of equine therapy on reducing symptoms of anxiety and depression in veterans with PTSD
• The role of nutrition in preventing and managing autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis
• The impact of job characteristics on work engagement and organizational commitment
• The relationship between cultural values and consumer behavior in the food industry
• The effects of virtual reality exposure therapy on treating depression in older adults
• The impact of mindfulness-based interventions on reducing burnout among healthcare professionals
• The relationship between financial literacy and retirement planning behavior
• The effectiveness of parent-child interaction therapy for young children with behavioral problems
• The role of physical activity in reducing symptoms of depression and anxiety in adults with chronic illnesses
• The effects of humor on stress reduction and well-being in the workplace
• The impact of cultural values on consumer decision-making in global markets
• The relationship between childhood adversity and adult romantic relationships
• The effectiveness of cognitive-behavioral therapy for substance use disorders
• The role of nutrition in promoting healthy gut microbiome and overall health
• The impact of inclusive hiring practices on workforce diversity and equity
• The relationship between self-compassion and mental health outcomes in young adults
• The effects of nature exposure on cognitive function and academic performance in children
• The role of physical activity in preventing and managing Type 2 diabetes
• The impact of social capital on community resilience in disaster-prone areas
• The relationship between emotional intelligence and leadership effectiveness in the workplace
• The effectiveness of eye movement desensitization and reprocessing therapy for posttraumatic stress disorder
• The role of nutrition in reducing the risk of cardiovascular disease
• The effects of cognitive-behavioral therapy for depression in individuals with chronic pain
• The impact of personality traits on financial decision-making and investment behavior
• The relationship between cultural values and consumer behavior in luxury markets
• The effects of virtual reality exposure therapy on treating panic disorder
• The role of physical activity in preventing and managing chronic obstructive pulmonary disease
• The impact of workplace diversity on organizational innovation and performance
• The relationship between self-esteem and academic achievement in college students
• The effects of animal-assisted therapy on reducing symptoms of anxiety in children with autism spectrum disorder
• The role of nutrition in promoting healthy skin and hair
• The effectiveness of cognitive-behavioral therapy for social anxiety disorder
• The impact of cultural intelligence on cross-cultural negotiation outcomes in international business
• The relationship between childhood adversity and adult mental health outcomes in the LGBTQ+ community
• The effects of gratitude practices on well-being and happiness in older adults
• The role of physical activity in reducing symptoms of depression and anxiety in pregnant women
• The impact of cultural values on social media use and behavior
• The relationship between self-compassion and workplace well-being and job satisfaction
• The effects of mindfulness on pain management and opioid use in individuals with chronic pain
• The role of nutrition in reducing the risk of stroke
• The impact of job crafting on employee engagement and performance in the workplace
• The relationship between personality and team dynamics in sports
• The effects of expressive writing on reducing symptoms of PTSD in military veterans
• The role of physical activity in preventing and managing asthma
• The impact of cultural differences on cross-cultural communication in international business
• The relationship between social support and emotional well-being in older adults
• The effects of virtual reality exposure therapy on treating generalized anxiety disorder
• The role of nutrition in promoting healthy brain development in infants and toddlers
• The impact of flexible work arrangements on work-life balance and family functioning
• The relationship between cultural values and attitudes towards aging and older adults
• The role of physical activity in preventing and managing chronic kidney disease
• The impact of climate change on food security in developing countries
• The relationship between social media use and body image dissatisfaction in adolescent girls
• The effectiveness of cognitive-behavioral therapy for eating disorders
• The role of physical activity in preventing and managing multiple sclerosis
• The impact of organizational culture on employee well-being and job satisfaction
• The relationship between personality and job performance in technology industries
• The effects of nature exposure on stress reduction and well-being
• The role of nutrition in reducing the risk of Alzheimer’s disease
• The effects of mindfulness on emotion regulation in individuals with bipolar disorder
• The relationship between cultural competence and healthcare disparities in marginalized communities
• The impact of sleep on academic achievement and cognitive function in college students
• The role of physical activity in preventing and managing rheumatoid arthritis
• The effects of creative arts therapy on reducing symptoms of depression and anxiety in cancer patients
• The relationship between parenting styles and adolescent mental health outcomes
• The impact of workplace incivility on employee well-being and turnover intentions
• The effects of meditation on executive function and attention in aging adults
• The relationship between personality and job performance in sales industries
• The effects of animal-assisted therapy on reducing symptoms of posttraumatic stress disorder in military veterans
• The impact of multiculturalism on social cohesion and intergroup relations in diverse societies
• The relationship between childhood trauma and adult physical health outcomes
• The role of nutrition in reducing the risk of breast cancer
• The impact of flexible work arrangements on employee motivation and job performance
• The relationship between social support and resilience in individuals with chronic illnesses
• The effects of yoga on stress reduction and mental health in pregnant women
• The role of physical activity in preventing and managing Parkinson’s disease
• The impact of cultural intelligence on intercultural competence in international business
• The relationship between adverse childhood experiences and adult financial well-being
• The effects of mindfulness on emotion regulation in individuals with borderline personality disorder
• The role of nutrition in reducing the risk of osteoarthritis
• The impact of organizational change on employee stress and job satisfaction
• The relationship between personality and job performance in human resources industries
• The effects of cognitive training on cognitive function and academic performance in aging adults
• The role of nutrition in promoting healthy bone development in children and adolescents
• The impact of supportive housing on mental health outcomes in individuals experiencing homelessness
• The relationship between exercise and cognitive function in individuals with multiple sclerosis
• The role of nutrition in reducing the risk of liver disease
• The impact of leadership styles on employee creativity and innovation in the workplace
• The relationship between childhood adversity and adult financial decision-making
• The effects of expressive writing on reducing symptoms of depression and anxiety in college students
• The role of physical activity in preventing and managing hypertension
• The impact of diversity and inclusion training on employee attitudes and behaviors in the workplace
• The relationship between personality and job satisfaction in hospitality industries.
• The impact of environmental factors on child development and academic achievement
• The relationship between cultural identity and mental health in immigrant populations
• The effectiveness of mindfulness-based cognitive therapy for depression
• The role of physical activity in preventing and managing type 2 diabetes
• The effects of music therapy on pain management in patients with chronic pain
• The impact of organizational justice on employee job satisfaction and organizational commitment
• The relationship between childhood obesity and adult health outcomes
• The effects of early childhood education on academic achievement and social skills in low-income communities
• The role of nutrition in preventing and managing autoimmune skin diseases
• The impact of work-life balance on employee well-being and job performance
• The relationship between adverse childhood experiences and adult substance use disorders
• The effects of virtual reality exposure therapy on anxiety and phobia treatment outcomes
• The effectiveness of mindfulness-based interventions for substance use disorders
• The role of physical activity in preventing and managing cardiovascular disease
• The impact of social support on mental health outcomes in individuals with chronic illnesses
• The relationship between personality and job performance in customer service fields
• The effects of art therapy on emotional regulation in individuals with personality disorders
• The role of nutrition in reducing the risk of depression in older adults
• The impact of workplace bullying on employee well-being and organizational outcomes
• The relationship between childhood adversity and adult mental health outcomes in marginalized communities
• The effectiveness of cognitive-behavioral therapy for panic disorder
• The effects of mindfulness on pain management in individuals with fibromyalgia
• The role of physical activity in preventing and managing osteoporosis
• The impact of cognitive-behavioral therapy on reducing suicide risk in adolescents
• The effects of cognitive training on cognitive function and academic performance in children with attention-deficit/hyperactivity disorder
• The role of nutrition in promoting healthy skin and preventing skin aging
• The impact of work-family policies on employee work-life balance and job satisfaction
• The relationship between childhood maltreatment and adult interpersonal relationships
• The effects of virtual reality exposure therapy on treating posttraumatic stress disorder in veterans
• The effectiveness of acceptance and commitment therapy for substance use disorders
• The impact of social support on mental health outcomes in caregivers of individuals with chronic illnesses
• The relationship between personality and job satisfaction in creative industries
• The effects of dance/movement therapy on emotional regulation and social skills in children with autism spectrum disorder
• The role of nutrition in reducing the risk of colorectal cancer
• The impact of inclusive leadership on employee diversity and inclusion attitudes in the workplace
• The relationship between social media use and mental health outcomes in college students
• The effectiveness of cognitive-behavioral therapy for generalized anxiety disorder
• The effects of mindfulness on sleep quality and quantity in individuals with insomnia
• The impact of peer support on mental health outcomes in individuals with schizophrenia
• The relationship between personality and job performance in healthcare fields
• The role of nutrition in promoting healthy gut microbiota and preventing gastrointestinal diseases
• The impact of flexible work arrangements on employee well-being and productivity
• The relationship between childhood trauma and adult attachment styles

About the author

Muhammad Hassan

Researcher, Academic Writer, Web developer

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Why Are Companies That Lose Money Still So Successful?

• Vijay Govindarajan,
• Shivaram Rajgopal,
• Anup Srivastava,
• Aneel Iqbal,
• Elnaz Basirian

New research on how to identify investments that produce delayed but real profits — not just those that produce short-term accounting profits.

In a well-functioning capital market, profits should be the sole criterion for firm survival; that is, firms reporting losses should disappear. Of late, however, loss-making firms are highly sought after by investors — often more than some profitable firms. Unicorns, or startups with valuations exceeding a billion dollars, are examples of such loss-making firms. What has changed over time? When and why did losses lose their meaning? The authors’ series of new research papers provide some answers, guiding managers to make the right investments: those that produce delayed but real profits — not just those that produce short-term accounting profits but decimate shareholder wealth in long run.

In 1979, psychologists Daniel Kahneman and Amos Tversky famously posited that losses loom larger than gains in human decision-making. For example, a dollar of loss affects our behavior more than a dollar of profits . Likewise, when a firm announces losses, its stock price declines more dramatically than it increases for the same dollar amount of profits. Investors abandon and lenders tend to stop financing loss-making firms , which then start restructuring their business lines and laying off employees. Some firms go even further, conducting M&A transactions without substance and “managing earnings” to report profits instead of a loss.

• Vijay Govindarajan is the Coxe Distinguished Professor at Dartmouth College’s Tuck School of Business, an executive fellow at Harvard Business School, and faculty partner at the Silicon Valley incubator Mach 49. He is a New York Times and Wall Street Journal bestselling author. His latest book is Fusion Strategy: How Real-Time Data and AI Will Power the Industrial Future . His Harvard Business Review articles “ Engineering Reverse Innovations ” and “ Stop the Innovation Wars ” won McKinsey Awards for best article published in HBR. His HBR articles “ How GE Is Disrupting Itself ” and “ The CEO’s Role in Business Model Reinvention ” are HBR all-time top-50 bestsellers. Follow him on LinkedIn . vgovindarajan
• Shivaram Rajgopal is the Roy Bernard Kester and T.W. Byrnes Professor of Accounting and Auditing and Vice Dean of Research at Columbia Business School. His research examines financial reporting and executive compensation issues and he is widely published in both accounting and finance.
• Anup Srivastava holds Canada Research Chair in Accounting, Decision Making, and Capital Markets and is a full professor at Haskayne School of Business, University of Calgary. In a series of HBR articles, he examines the management implications of digital disruption. He specializes in the valuation and financial reporting challenges of digital companies. Follow Anup on  LinkedIn .
• Aneel Iqbal is an assistant professor at Thunderbird School of Global Management, Arizona State University. He examines the accounting measurement and financial disclosures for new-economy firms and incorporates his wide-ranging industry experience into his research and teaching. He is a seasoned accounting and finance professional with diverse experience in auditing, financial analysis, business advisory, performance management, and executive training. Follow Aneel on LinkedIn .
• Elnaz Basirian is a PhD student at the Haskayne School of Business. She examines the influence and role of intangibles in accounting and finance, aimed at improving valuation and market efficiency. She brings a decade of work experience in international financial markets. Follow Elnaz on LinkedIn .

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Research Topics & Ideas: Education

170+ Research Ideas To Fast-Track Your Project

If you’re just starting out exploring education-related topics for your dissertation, thesis or research project, you’ve come to the right place. In this post, we’ll help kickstart your research topic ideation process by providing a hearty list of research topics and ideas , including examples from actual dissertations and theses..

PS – This is just the start…

We know it’s exciting to run through a list of research topics, but please keep in mind that this list is just a starting point . To develop a suitable education-related research topic, you’ll need to identify a clear and convincing research gap , and a viable plan of action to fill that gap.

If this sounds foreign to you, check out our free research topic webinar that explores how to find and refine a high-quality research topic, from scratch. Alternatively, if you’d like hands-on help, consider our 1-on-1 coaching service .

Overview: Education Research Topics

• How to find a research topic (video)
• List of 50+ education-related research topics/ideas
• List of 120+ level-specific research topics 
• Examples of actual dissertation topics in education
• Tips to fast-track your topic ideation (video)
• Free Webinar : Topic Ideation 101
• Where to get extra help

Education-Related Research Topics & Ideas

Below you’ll find a list of education-related research topics and idea kickstarters. These are fairly broad and flexible to various contexts, so keep in mind that you will need to refine them a little. Nevertheless, they should inspire some ideas for your project.

• The impact of school funding on student achievement
• The effects of social and emotional learning on student well-being
• The effects of parental involvement on student behaviour
• The impact of teacher training on student learning
• The impact of classroom design on student learning
• The impact of poverty on education
• The use of student data to inform instruction
• The role of parental involvement in education
• The effects of mindfulness practices in the classroom
• The use of technology in the classroom
• The role of critical thinking in education
• The use of formative and summative assessments in the classroom
• The use of differentiated instruction in the classroom
• The use of gamification in education
• The effects of teacher burnout on student learning
• The impact of school leadership on student achievement
• The effects of teacher diversity on student outcomes
• The role of teacher collaboration in improving student outcomes
• The implementation of blended and online learning
• The effects of teacher accountability on student achievement
• The effects of standardized testing on student learning
• The effects of classroom management on student behaviour
• The effects of school culture on student achievement
• The use of student-centred learning in the classroom
• The impact of teacher-student relationships on student outcomes
• The achievement gap in minority and low-income students
• The use of culturally responsive teaching in the classroom
• The impact of teacher professional development on student learning
• The use of project-based learning in the classroom
• The effects of teacher expectations on student achievement
• The use of adaptive learning technology in the classroom
• The impact of teacher turnover on student learning
• The effects of teacher recruitment and retention on student learning
• The impact of early childhood education on later academic success
• The impact of parental involvement on student engagement
• The use of positive reinforcement in education
• The impact of school climate on student engagement
• The role of STEM education in preparing students for the workforce
• The effects of school choice on student achievement
• The use of technology in the form of online tutoring

Level-Specific Research Topics

Looking for research topics for a specific level of education? We’ve got you covered. Below you can find research topic ideas for primary, secondary and tertiary-level education contexts. Click the relevant level to view the respective list.

Research Topics: Pick An Education Level

Primary education.

• Investigating the effects of peer tutoring on academic achievement in primary school
• Exploring the benefits of mindfulness practices in primary school classrooms
• Examining the effects of different teaching strategies on primary school students’ problem-solving skills
• The use of storytelling as a teaching strategy in primary school literacy instruction
• The role of cultural diversity in promoting tolerance and understanding in primary schools
• The impact of character education programs on moral development in primary school students
• Investigating the use of technology in enhancing primary school mathematics education
• The impact of inclusive curriculum on promoting equity and diversity in primary schools
• The impact of outdoor education programs on environmental awareness in primary school students
• The influence of school climate on student motivation and engagement in primary schools
• Investigating the effects of early literacy interventions on reading comprehension in primary school students
• The impact of parental involvement in school decision-making processes on student achievement in primary schools
• Exploring the benefits of inclusive education for students with special needs in primary schools
• Investigating the effects of teacher-student feedback on academic motivation in primary schools
• The role of technology in developing digital literacy skills in primary school students
• Effective strategies for fostering a growth mindset in primary school students
• Investigating the role of parental support in reducing academic stress in primary school children
• The role of arts education in fostering creativity and self-expression in primary school students
• Examining the effects of early childhood education programs on primary school readiness
• Examining the effects of homework on primary school students’ academic performance
• The role of formative assessment in improving learning outcomes in primary school classrooms
• The impact of teacher-student relationships on academic outcomes in primary school
• Investigating the effects of classroom environment on student behavior and learning outcomes in primary schools
• Investigating the role of creativity and imagination in primary school curriculum
• The impact of nutrition and healthy eating programs on academic performance in primary schools
• The impact of social-emotional learning programs on primary school students’ well-being and academic performance
• The role of parental involvement in academic achievement of primary school children
• Examining the effects of classroom management strategies on student behavior in primary school
• The role of school leadership in creating a positive school climate Exploring the benefits of bilingual education in primary schools
• The effectiveness of project-based learning in developing critical thinking skills in primary school students
• The role of inquiry-based learning in fostering curiosity and critical thinking in primary school students
• The effects of class size on student engagement and achievement in primary schools
• Investigating the effects of recess and physical activity breaks on attention and learning in primary school
• Exploring the benefits of outdoor play in developing gross motor skills in primary school children
• The effects of educational field trips on knowledge retention in primary school students
• Examining the effects of inclusive classroom practices on students’ attitudes towards diversity in primary schools
• The impact of parental involvement in homework on primary school students’ academic achievement
• Investigating the effectiveness of different assessment methods in primary school classrooms
• The influence of physical activity and exercise on cognitive development in primary school children
• Exploring the benefits of cooperative learning in promoting social skills in primary school students

Secondary Education

• Investigating the effects of school discipline policies on student behavior and academic success in secondary education
• The role of social media in enhancing communication and collaboration among secondary school students
• The impact of school leadership on teacher effectiveness and student outcomes in secondary schools
• Investigating the effects of technology integration on teaching and learning in secondary education
• Exploring the benefits of interdisciplinary instruction in promoting critical thinking skills in secondary schools
• The impact of arts education on creativity and self-expression in secondary school students
• The effectiveness of flipped classrooms in promoting student learning in secondary education
• The role of career guidance programs in preparing secondary school students for future employment
• Investigating the effects of student-centered learning approaches on student autonomy and academic success in secondary schools
• The impact of socio-economic factors on educational attainment in secondary education
• Investigating the impact of project-based learning on student engagement and academic achievement in secondary schools
• Investigating the effects of multicultural education on cultural understanding and tolerance in secondary schools
• The influence of standardized testing on teaching practices and student learning in secondary education
• Investigating the effects of classroom management strategies on student behavior and academic engagement in secondary education
• The influence of teacher professional development on instructional practices and student outcomes in secondary schools
• The role of extracurricular activities in promoting holistic development and well-roundedness in secondary school students
• Investigating the effects of blended learning models on student engagement and achievement in secondary education
• The role of physical education in promoting physical health and well-being among secondary school students
• Investigating the effects of gender on academic achievement and career aspirations in secondary education
• Exploring the benefits of multicultural literature in promoting cultural awareness and empathy among secondary school students
• The impact of school counseling services on student mental health and well-being in secondary schools
• Exploring the benefits of vocational education and training in preparing secondary school students for the workforce
• The role of digital literacy in preparing secondary school students for the digital age
• The influence of parental involvement on academic success and well-being of secondary school students
• The impact of social-emotional learning programs on secondary school students’ well-being and academic success
• The role of character education in fostering ethical and responsible behavior in secondary school students
• Examining the effects of digital citizenship education on responsible and ethical technology use among secondary school students
• The impact of parental involvement in school decision-making processes on student outcomes in secondary schools
• The role of educational technology in promoting personalized learning experiences in secondary schools
• The impact of inclusive education on the social and academic outcomes of students with disabilities in secondary schools
• The influence of parental support on academic motivation and achievement in secondary education
• The role of school climate in promoting positive behavior and well-being among secondary school students
• Examining the effects of peer mentoring programs on academic achievement and social-emotional development in secondary schools
• Examining the effects of teacher-student relationships on student motivation and achievement in secondary schools
• Exploring the benefits of service-learning programs in promoting civic engagement among secondary school students
• The impact of educational policies on educational equity and access in secondary education
• Examining the effects of homework on academic achievement and student well-being in secondary education
• Investigating the effects of different assessment methods on student performance in secondary schools
• Examining the effects of single-sex education on academic performance and gender stereotypes in secondary schools
• The role of mentoring programs in supporting the transition from secondary to post-secondary education

Tertiary Education

• The role of student support services in promoting academic success and well-being in higher education
• The impact of internationalization initiatives on students’ intercultural competence and global perspectives in tertiary education
• Investigating the effects of active learning classrooms and learning spaces on student engagement and learning outcomes in tertiary education
• Exploring the benefits of service-learning experiences in fostering civic engagement and social responsibility in higher education
• The influence of learning communities and collaborative learning environments on student academic and social integration in higher education
• Exploring the benefits of undergraduate research experiences in fostering critical thinking and scientific inquiry skills
• Investigating the effects of academic advising and mentoring on student retention and degree completion in higher education
• The role of student engagement and involvement in co-curricular activities on holistic student development in higher education
• The impact of multicultural education on fostering cultural competence and diversity appreciation in higher education
• The role of internships and work-integrated learning experiences in enhancing students’ employability and career outcomes
• Examining the effects of assessment and feedback practices on student learning and academic achievement in tertiary education
• The influence of faculty professional development on instructional practices and student outcomes in tertiary education
• The influence of faculty-student relationships on student success and well-being in tertiary education
• The impact of college transition programs on students’ academic and social adjustment to higher education
• The impact of online learning platforms on student learning outcomes in higher education
• The impact of financial aid and scholarships on access and persistence in higher education
• The influence of student leadership and involvement in extracurricular activities on personal development and campus engagement
• Exploring the benefits of competency-based education in developing job-specific skills in tertiary students
• Examining the effects of flipped classroom models on student learning and retention in higher education
• Exploring the benefits of online collaboration and virtual team projects in developing teamwork skills in tertiary students
• Investigating the effects of diversity and inclusion initiatives on campus climate and student experiences in tertiary education
• The influence of study abroad programs on intercultural competence and global perspectives of college students
• Investigating the effects of peer mentoring and tutoring programs on student retention and academic performance in tertiary education
• Investigating the effectiveness of active learning strategies in promoting student engagement and achievement in tertiary education
• Investigating the effects of blended learning models and hybrid courses on student learning and satisfaction in higher education
• The role of digital literacy and information literacy skills in supporting student success in the digital age
• Investigating the effects of experiential learning opportunities on career readiness and employability of college students
• The impact of e-portfolios on student reflection, self-assessment, and showcasing of learning in higher education
• The role of technology in enhancing collaborative learning experiences in tertiary classrooms
• The impact of research opportunities on undergraduate student engagement and pursuit of advanced degrees
• Examining the effects of competency-based assessment on measuring student learning and achievement in tertiary education
• Examining the effects of interdisciplinary programs and courses on critical thinking and problem-solving skills in college students
• The role of inclusive education and accessibility in promoting equitable learning experiences for diverse student populations
• The role of career counseling and guidance in supporting students’ career decision-making in tertiary education
• The influence of faculty diversity and representation on student success and inclusive learning environments in higher education

Education-Related Dissertations & Theses

While the ideas we’ve presented above are a decent starting point for finding a research topic in education, they are fairly generic and non-specific. So, it helps to look at actual dissertations and theses in the education space to see how this all comes together in practice.

Below, we’ve included a selection of education-related research projects to help refine your thinking. These are actual dissertations and theses, written as part of Master’s and PhD-level programs, so they can provide some useful insight as to what a research topic looks like in practice.

• From Rural to Urban: Education Conditions of Migrant Children in China (Wang, 2019)
• Energy Renovation While Learning English: A Guidebook for Elementary ESL Teachers (Yang, 2019)
• A Reanalyses of Intercorrelational Matrices of Visual and Verbal Learners’ Abilities, Cognitive Styles, and Learning Preferences (Fox, 2020)
• A study of the elementary math program utilized by a mid-Missouri school district (Barabas, 2020)
• Instructor formative assessment practices in virtual learning environments : a posthumanist sociomaterial perspective (Burcks, 2019)
• Higher education students services: a qualitative study of two mid-size universities’ direct exchange programs (Kinde, 2020)
• Exploring editorial leadership : a qualitative study of scholastic journalism advisers teaching leadership in Missouri secondary schools (Lewis, 2020)
• Selling the virtual university: a multimodal discourse analysis of marketing for online learning (Ludwig, 2020)
• Advocacy and accountability in school counselling: assessing the use of data as related to professional self-efficacy (Matthews, 2020)
• The use of an application screening assessment as a predictor of teaching retention at a midwestern, K-12, public school district (Scarbrough, 2020)
• Core values driving sustained elite performance cultures (Beiner, 2020)
• Educative features of upper elementary Eureka math curriculum (Dwiggins, 2020)
• How female principals nurture adult learning opportunities in successful high schools with challenging student demographics (Woodward, 2020)
• The disproportionality of Black Males in Special Education: A Case Study Analysis of Educator Perceptions in a Southeastern Urban High School (McCrae, 2021)

As you can see, these research topics are a lot more focused than the generic topic ideas we presented earlier. So, in order for you to develop a high-quality research topic, you’ll need to get specific and laser-focused on a specific context with specific variables of interest.  In the video below, we explore some other important things you’ll need to consider when crafting your research topic.

Get 1-On-1 Help

If you’re still unsure about how to find a quality research topic within education, check out our Research Topic Kickstarter service, which is the perfect starting point for developing a unique, well-justified research topic.

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66 Comments

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Special education

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Research title related to school of students

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Research title related to students

My field is research measurement and evaluation. Need dissertation topics in the field

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Good idea I’m going to teach my colleagues

You can find our list of nursing-related research topic ideas here: https://gradcoach.com/research-topics-nursing/

Write on action research topic, using guidance and counseling to address unwanted teenage pregnancy in school

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parental involvement and students academic performance

Science education topics?

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Kindly help me with the research questions on the topic” Effects of workplace conflict on the employees’ job performance”. The effects can be applicable in every institution,enterprise or organisation.

Greetings, I am a student majoring in Sociology and minoring in Public Administration. I’m considering any recommended research topic in the field of Sociology.

I’m a student pursuing Mphil in Basic education and I’m considering any recommended research proposal topic in my field of study

Research Defense for students in senior high

Kindly help me with a research topic in educational psychology. Ph.D level. Thank you.

Project-based learning is a teaching/learning type,if well applied in a classroom setting will yield serious positive impact. What can a teacher do to implement this in a disadvantaged zone like “North West Region of Cameroon ( hinterland) where war has brought about prolonged and untold sufferings on the indegins?

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I wish to get help on topics of research on educational administration PhD level

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Would like to request for suggestions on a topic in Economics of education,PhD level

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request suggestion on topic in masters in medical education .

Look at British Library as they keep a copy of all PhDs in the UK Core.ac.uk to access Open University and 6 other university e-archives, pdf downloads mostly available, all free.

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Please I am a masters student of the department of Teacher Education, Faculty of Education Please I am in need of proposed project topics to help with my final year thesis

Am a PhD student in Educational Foundations would like a sociological topic. Thank

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Masters student in the field of curriculum, any ideas of a research topic on low achiever students

In the field of curriculum any ideas of a research topic on deconalization in contextualization of digital teaching and learning through in higher education

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I am a graduate with two masters. 1) Master of arts in religious studies and 2) Master in education in foundations of education. I intend to do a Ph.D. on my second master’s, however, I need to bring both masters together through my Ph.D. research. can I do something like, ” The contribution of Philosophy of education for a quality religion education in Kenya”? kindly, assist and be free to suggest a similar topic that will bring together the two masters. thanks in advance

Hi, I am an Early childhood trainer as well as a researcher, I need more support on this topic: The impact of early childhood education on later academic success.

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Sat / act prep online guides and tips, 113 great research paper topics.

General Education

One of the hardest parts of writing a research paper can be just finding a good topic to write about. Fortunately we've done the hard work for you and have compiled a list of 113 interesting research paper topics. They've been organized into ten categories and cover a wide range of subjects so you can easily find the best topic for you.

In addition to the list of good research topics, we've included advice on what makes a good research paper topic and how you can use your topic to start writing a great paper.

What Makes a Good Research Paper Topic?

Not all research paper topics are created equal, and you want to make sure you choose a great topic before you start writing. Below are the three most important factors to consider to make sure you choose the best research paper topics.

#1: It's Something You're Interested In

A paper is always easier to write if you're interested in the topic, and you'll be more motivated to do in-depth research and write a paper that really covers the entire subject. Even if a certain research paper topic is getting a lot of buzz right now or other people seem interested in writing about it, don't feel tempted to make it your topic unless you genuinely have some sort of interest in it as well.

#2: There's Enough Information to Write a Paper

Even if you come up with the absolute best research paper topic and you're so excited to write about it, you won't be able to produce a good paper if there isn't enough research about the topic. This can happen for very specific or specialized topics, as well as topics that are too new to have enough research done on them at the moment. Easy research paper topics will always be topics with enough information to write a full-length paper.

Trying to write a research paper on a topic that doesn't have much research on it is incredibly hard, so before you decide on a topic, do a bit of preliminary searching and make sure you'll have all the information you need to write your paper.

#3: It Fits Your Teacher's Guidelines

Don't get so carried away looking at lists of research paper topics that you forget any requirements or restrictions your teacher may have put on research topic ideas. If you're writing a research paper on a health-related topic, deciding to write about the impact of rap on the music scene probably won't be allowed, but there may be some sort of leeway. For example, if you're really interested in current events but your teacher wants you to write a research paper on a history topic, you may be able to choose a topic that fits both categories, like exploring the relationship between the US and North Korea. No matter what, always get your research paper topic approved by your teacher first before you begin writing.

113 Good Research Paper Topics

Below are 113 good research topics to help you get you started on your paper. We've organized them into ten categories to make it easier to find the type of research paper topics you're looking for.

Arts/Culture

• Discuss the main differences in art from the Italian Renaissance and the Northern Renaissance .
• Analyze the impact a famous artist had on the world.
• How is sexism portrayed in different types of media (music, film, video games, etc.)? Has the amount/type of sexism changed over the years?
• How has the music of slaves brought over from Africa shaped modern American music?
• How has rap music evolved in the past decade?
• How has the portrayal of minorities in the media changed?

Current Events

• What have been the impacts of China's one child policy?
• How have the goals of feminists changed over the decades?
• How has the Trump presidency changed international relations?
• Analyze the history of the relationship between the United States and North Korea.
• What factors contributed to the current decline in the rate of unemployment?
• What have been the impacts of states which have increased their minimum wage?
• How do US immigration laws compare to immigration laws of other countries?
• How have the US's immigration laws changed in the past few years/decades?
• How has the Black Lives Matter movement affected discussions and view about racism in the US?
• What impact has the Affordable Care Act had on healthcare in the US?
• What factors contributed to the UK deciding to leave the EU (Brexit)?
• What factors contributed to China becoming an economic power?
• Discuss the history of Bitcoin or other cryptocurrencies  (some of which tokenize the S&P 500 Index on the blockchain) .
• Do students in schools that eliminate grades do better in college and their careers?
• Do students from wealthier backgrounds score higher on standardized tests?
• Do students who receive free meals at school get higher grades compared to when they weren't receiving a free meal?
• Do students who attend charter schools score higher on standardized tests than students in public schools?
• Do students learn better in same-sex classrooms?
• How does giving each student access to an iPad or laptop affect their studies?
• What are the benefits and drawbacks of the Montessori Method ?
• Do children who attend preschool do better in school later on?
• What was the impact of the No Child Left Behind act?
• How does the US education system compare to education systems in other countries?
• What impact does mandatory physical education classes have on students' health?
• Which methods are most effective at reducing bullying in schools?
• Do homeschoolers who attend college do as well as students who attended traditional schools?
• Does offering tenure increase or decrease quality of teaching?
• How does college debt affect future life choices of students?
• Should graduate students be able to form unions?

• What are different ways to lower gun-related deaths in the US?
• How and why have divorce rates changed over time?
• Is affirmative action still necessary in education and/or the workplace?
• Should physician-assisted suicide be legal?
• How has stem cell research impacted the medical field?
• How can human trafficking be reduced in the United States/world?
• Should people be able to donate organs in exchange for money?
• Which types of juvenile punishment have proven most effective at preventing future crimes?
• Has the increase in US airport security made passengers safer?
• Analyze the immigration policies of certain countries and how they are similar and different from one another.
• Several states have legalized recreational marijuana. What positive and negative impacts have they experienced as a result?
• Do tariffs increase the number of domestic jobs?
• Which prison reforms have proven most effective?
• Should governments be able to censor certain information on the internet?
• Which methods/programs have been most effective at reducing teen pregnancy?
• What are the benefits and drawbacks of the Keto diet?
• How effective are different exercise regimes for losing weight and maintaining weight loss?
• How do the healthcare plans of various countries differ from each other?
• What are the most effective ways to treat depression ?
• What are the pros and cons of genetically modified foods?
• Which methods are most effective for improving memory?
• What can be done to lower healthcare costs in the US?
• What factors contributed to the current opioid crisis?
• Analyze the history and impact of the HIV/AIDS epidemic .
• Are low-carbohydrate or low-fat diets more effective for weight loss?
• How much exercise should the average adult be getting each week?
• Which methods are most effective to get parents to vaccinate their children?
• What are the pros and cons of clean needle programs?
• How does stress affect the body?
• Discuss the history of the conflict between Israel and the Palestinians.
• What were the causes and effects of the Salem Witch Trials?
• Who was responsible for the Iran-Contra situation?
• How has New Orleans and the government's response to natural disasters changed since Hurricane Katrina?
• What events led to the fall of the Roman Empire?
• What were the impacts of British rule in India ?
• Was the atomic bombing of Hiroshima and Nagasaki necessary?
• What were the successes and failures of the women's suffrage movement in the United States?
• What were the causes of the Civil War?
• How did Abraham Lincoln's assassination impact the country and reconstruction after the Civil War?
• Which factors contributed to the colonies winning the American Revolution?
• What caused Hitler's rise to power?
• Discuss how a specific invention impacted history.
• What led to Cleopatra's fall as ruler of Egypt?
• How has Japan changed and evolved over the centuries?
• What were the causes of the Rwandan genocide ?

• Why did Martin Luther decide to split with the Catholic Church?
• Analyze the history and impact of a well-known cult (Jonestown, Manson family, etc.)
• How did the sexual abuse scandal impact how people view the Catholic Church?
• How has the Catholic church's power changed over the past decades/centuries?
• What are the causes behind the rise in atheism/ agnosticism in the United States?
• What were the influences in Siddhartha's life resulted in him becoming the Buddha?
• How has media portrayal of Islam/Muslims changed since September 11th?

Science/Environment

• How has the earth's climate changed in the past few decades?
• How has the use and elimination of DDT affected bird populations in the US?
• Analyze how the number and severity of natural disasters have increased in the past few decades.
• Analyze deforestation rates in a certain area or globally over a period of time.
• How have past oil spills changed regulations and cleanup methods?
• How has the Flint water crisis changed water regulation safety?
• What are the pros and cons of fracking?
• What impact has the Paris Climate Agreement had so far?
• What have NASA's biggest successes and failures been?
• How can we improve access to clean water around the world?
• Does ecotourism actually have a positive impact on the environment?
• Should the US rely on nuclear energy more?
• What can be done to save amphibian species currently at risk of extinction?
• What impact has climate change had on coral reefs?
• How are black holes created?
• Are teens who spend more time on social media more likely to suffer anxiety and/or depression?
• How will the loss of net neutrality affect internet users?
• Analyze the history and progress of self-driving vehicles.
• How has the use of drones changed surveillance and warfare methods?
• Has social media made people more or less connected?
• What progress has currently been made with artificial intelligence ?
• Do smartphones increase or decrease workplace productivity?
• What are the most effective ways to use technology in the classroom?
• How is Google search affecting our intelligence?
• When is the best age for a child to begin owning a smartphone?
• Has frequent texting reduced teen literacy rates?

How to Write a Great Research Paper

Even great research paper topics won't give you a great research paper if you don't hone your topic before and during the writing process. Follow these three tips to turn good research paper topics into great papers.

#1: Figure Out Your Thesis Early

Before you start writing a single word of your paper, you first need to know what your thesis will be. Your thesis is a statement that explains what you intend to prove/show in your paper. Every sentence in your research paper will relate back to your thesis, so you don't want to start writing without it!

As some examples, if you're writing a research paper on if students learn better in same-sex classrooms, your thesis might be "Research has shown that elementary-age students in same-sex classrooms score higher on standardized tests and report feeling more comfortable in the classroom."

If you're writing a paper on the causes of the Civil War, your thesis might be "While the dispute between the North and South over slavery is the most well-known cause of the Civil War, other key causes include differences in the economies of the North and South, states' rights, and territorial expansion."

#2: Back Every Statement Up With Research

Remember, this is a research paper you're writing, so you'll need to use lots of research to make your points. Every statement you give must be backed up with research, properly cited the way your teacher requested. You're allowed to include opinions of your own, but they must also be supported by the research you give.

#3: Do Your Research Before You Begin Writing

You don't want to start writing your research paper and then learn that there isn't enough research to back up the points you're making, or, even worse, that the research contradicts the points you're trying to make!

Get most of your research on your good research topics done before you begin writing. Then use the research you've collected to create a rough outline of what your paper will cover and the key points you're going to make. This will help keep your paper clear and organized, and it'll ensure you have enough research to produce a strong paper.

What's Next?

Are you also learning about dynamic equilibrium in your science class? We break this sometimes tricky concept down so it's easy to understand in our complete guide to dynamic equilibrium .

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Christine graduated from Michigan State University with degrees in Environmental Biology and Geography and received her Master's from Duke University. In high school she scored in the 99th percentile on the SAT and was named a National Merit Finalist. She has taught English and biology in several countries.

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61 intriguing psychology research topics to explore

Last updated

11 January 2024

Reviewed by

Brittany Ferri, PhD, OTR/L

Short on time? Get an AI generated summary of this article instead

Psychology is an incredibly diverse, critical, and ever-changing area of study in the medical and health industries. Because of this, it’s a common area of study for students and healthcare professionals.

We’re walking you through picking the perfect topic for your upcoming paper or study. Keep reading for plenty of example topics to pique your interest and curiosity.

• How to choose a psychology research topic

Exploring a psychology-based topic for your research project? You need to pick a specific area of interest to collect compelling data. 

Use these tips to help you narrow down which psychology topics to research:

Focus on a particular area of psychology

The most effective psychological research focuses on a smaller, niche concept or disorder within the scope of a study. 

Psychology is a broad and fascinating area of science, including everything from diagnosed mental health disorders to sports performance mindset assessments. 

This gives you plenty of different avenues to explore. Having a hard time choosing? Check out our list of 61 ideas further down in this article to get started.

Read the latest clinical studies

Once you’ve picked a more niche topic to explore, you need to do your due diligence and explore other research projects on the same topic. 

This practice will help you learn more about your chosen topic, ask more specific questions, and avoid covering existing projects. 

For the best results, we recommend creating a research folder of associated published papers to reference throughout your project. This makes it much easier to cite direct references and find inspiration down the line.

Find a topic you enjoy and ask questions

Once you’ve spent time researching and collecting references for your study, you finally get to explore. 

Whether this research project is for work, school, or just for fun, having a passion for your research will make the project much more enjoyable. (Trust us, there will be times when that is the only thing that keeps you going.) 

Now you’ve decided on the topic, ask more nuanced questions you might want to explore. 

If you can, pick the direction that interests you the most to make the research process much more enjoyable.

• 61 psychology topics to research in 2024

Need some extra help starting your psychology research project on the right foot? Explore our list of 61 cutting-edge, in-demand psychology research topics to use as a starting point for your research journey.

• Psychology research topics for university students

As a university student, it can be hard to pick a research topic that fits the scope of your classes and is still compelling and unique. 

Here are a few exciting topics we recommend exploring for your next assigned research project:

Mental health in post-secondary students

Seeking post-secondary education is a stressful and overwhelming experience for most students, making this topic a great choice to explore for your in-class research paper. 

Examples of post-secondary mental health research topics include:

Student mental health status during exam season

Mental health disorder prevalence based on study major

The impact of chronic school stress on overall quality of life

The impacts of cyberbullying

Cyberbullying can occur at all ages, starting as early as elementary school and carrying through into professional workplaces. 

Examples of cyberbullying-based research topics you can study include:

The impact of cyberbullying on self-esteem

Common reasons people engage in cyberbullying 

Cyberbullying themes and commonly used terms

Cyberbullying habits in children vs. adults

The long-term effects of cyberbullying

• Clinical psychology research topics

If you’re looking to take a more clinical approach to your next project, here are a few topics that involve direct patient assessment for you to consider:

Chronic pain and mental health

Living with chronic pain dramatically impacts every aspect of a person’s life, including their mental and emotional health. 

Here are a few examples of in-demand pain-related psychology research topics:

The connection between diabetic neuropathy and depression

Neurological pain and its connection to mental health disorders

Efficacy of meditation and mindfulness for pain management

The long-term effects of insomnia

Insomnia is where you have difficulty falling or staying asleep. It’s a common health concern that impacts millions of people worldwide. 

This is an excellent topic because insomnia can have a variety of causes, offering many research possibilities. 

Here are a few compelling psychology research topics about insomnia you could investigate:

The prevalence of insomnia based on age, gender, and ethnicity

Insomnia and its impact on workplace productivity

The connection between insomnia and mental health disorders

Efficacy and use of melatonin supplements for insomnia

The risks and benefits of prescription insomnia medications

Lifestyle options for managing insomnia symptoms

The efficacy of mental health treatment options

Management and treatment of mental health conditions is an ever-changing area of study. If you can witness or participate in mental health therapies, this can make a great research project. 

Examples of mental health treatment-related psychology research topics include:

The efficacy of cognitive behavioral therapy (CBT) for patients with severe anxiety

The benefits and drawbacks of group vs. individual therapy sessions

Music therapy for mental health disorders

Electroconvulsive therapy (ECT) for patients with depression 

• Controversial psychology research paper topics

If you are looking to explore a more cutting-edge or modern psychology topic, you can delve into a variety of controversial and topical options:

The impact of social media and digital platforms

Ever since access to internet forums and video games became more commonplace, there’s been growing concern about the impact these digital platforms have on mental health. 

Examples of social media and video game-related psychology research topics include:

The effect of edited images on self-confidence

How social media platforms impact social behavior

Video games and their impact on teenage anger and violence

Digital communication and the rapid spread of misinformation

The development of digital friendships

Psychotropic medications for mental health

In recent years, the interest in using psychoactive medications to treat and manage health conditions has increased despite their inherently controversial nature. 

Examples of psychotropic medication-related research topics include:

The risks and benefits of using psilocybin mushrooms for managing anxiety

The impact of marijuana on early-onset psychosis

Childhood marijuana use and related prevalence of mental health conditions

Ketamine and its use for complex PTSD (C-PTSD) symptom management

The effect of long-term psychedelic use and mental health conditions

• Mental health disorder research topics

As one of the most popular subsections of psychology, studying mental health disorders and how they impact quality of life is an essential and impactful area of research. 

While studies in these areas are common, there’s always room for additional exploration, including the following hot-button topics:

Anxiety and depression disorders

Anxiety and depression are well-known and heavily researched mental health disorders. 

Despite this, we still don’t know many things about these conditions, making them great candidates for psychology research projects:

Social anxiety and its connection to chronic loneliness

C-PTSD symptoms and causes

The development of phobias

Obsessive-compulsive disorder (OCD) behaviors and symptoms

Depression triggers and causes

Self-care tools and resources for depression

The prevalence of anxiety and depression in particular age groups or geographic areas

Bipolar disorder

Bipolar disorder is a complex and multi-faceted area of psychology research. 

Use your research skills to learn more about this condition and its impact by choosing any of the following topics:

Early signs of bipolar disorder

The incidence of bipolar disorder in young adults

The efficacy of existing bipolar treatment options

Bipolar medication side effects

Cognitive behavioral therapy for people with bipolar 

Schizoaffective disorder

Schizoaffective disorder is often stigmatized, and less common mental health disorders are a hotbed for new and exciting research. 

Here are a few examples of interesting research topics related to this mental health disorder:

The prevalence of schizoaffective disorder by certain age groups or geographic locations

Risk factors for developing schizoaffective disorder

The prevalence and content of auditory and visual hallucinations

Alternative therapies for schizoaffective disorder

• Societal and systematic psychology research topics

Modern society’s impact is deeply enmeshed in our mental and emotional health on a personal and community level. 

Here are a few examples of societal and systemic psychology research topics to explore in more detail:

Access to mental health services

While mental health awareness has risen over the past few decades, access to quality mental health treatment and resources is still not equitable. 

This can significantly impact the severity of a person’s mental health symptoms, which can result in worse health outcomes if left untreated. 

Explore this crucial issue and provide information about the need for improved mental health resource access by studying any of the following topics:

Rural vs. urban access to mental health resources

Access to crisis lines by location

Wait times for emergency mental health services

Inequities in mental health access based on income and location

Insurance coverage for mental health services

Systemic racism and mental health

Societal systems and the prevalence of systemic racism heavily impact every aspect of a person’s overall health.

Researching these topics draws attention to existing problems and contributes valuable insights into ways to improve access to care moving forward.

Examples of systemic racism-related psychology research topics include: 

Access to mental health resources based on race

The prevalence of BIPOC mental health therapists in a chosen area

The impact of systemic racism on mental health and self-worth

Racism training for mental health workers

The prevalence of mental health disorders in discriminated groups

LGBTQIA+ mental health concerns

Research about LGBTQIA+ people and their mental health needs is a unique area of study to explore for your next research project. It’s a commonly overlooked and underserved community.

Examples of LGBTQIA+ psychology research topics to consider include:

Mental health supports for queer teens and children

The impact of queer safe spaces on mental health

The prevalence of mental health disorders in the LGBTQIA+ community

The benefits of queer mentorship and found family

Substance misuse in LQBTQIA+ youth and adults

• Collect data and identify trends with Dovetail

Psychology research is an exciting and competitive study area, making it the perfect choice for projects or papers.

Take the headache out of analyzing your data and instantly access the insights you need to complete your next psychology research project by teaming up with Dovetail today.

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• Research into trans medicine has been manipulated

Court documents offer a window into how this happens

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I N APRIL HILARY CASS , a British paediatrician, published her review of gender-identity services for children and young people, commissioned by NHS England. It cast doubt on the evidence base for youth gender medicine. This prompted the World Professional Association for Transgender Health ( WPATH ), the leading professional organisation for the doctors and practitioners who provide services to trans people, to release a blistering rejoinder. WPATH said that its own guidelines were sturdier, in part because they were “based on far more systematic reviews”.

Systematic reviews should evaluate the evidence for a given medical question in a careful, rigorous manner. Such efforts are particularly important at the moment, given the feverish state of the American debate on youth gender medicine, which is soon to culminate in a Supreme Court case challenging a ban in Tennessee. The case turns, in part, on questions of evidence and expert authority.

Court documents recently released as part of the discovery process in a case involving youth gender medicine in Alabama reveal that WPATH ’s claim was built on shaky foundations. The documents show that the organisation’s leaders interfered with the production of systematic reviews that it had commissioned from the Johns Hopkins University Evidence-Based Practice Centre ( EPC ) in 2018.

From early on in the contract negotiations, WPATH expressed a desire to control the results of the Hopkins team’s work. In December 2017, for example, Donna Kelly, an executive director at WPATH , told Karen Robinson, the EPC ’s director, that the WPATH board felt the EPC researchers “cannot publish their findings independently”. A couple of weeks later, Ms Kelly emphasised that, “the [ WPATH ] board wants it to be clear that the data cannot be used without WPATH approval”.

Ms Robinson saw this as an attempt to exert undue influence over what was supposed to be an independent process. John Ioannidis of Stanford University, who co-authored guidelines for systematic reviews, says that if sponsors interfere or are allowed to veto results, this can lead to either biased summaries or suppression of unfavourable evidence. Ms Robinson sought to avoid such an outcome. “In general, my understanding is that the university will not sign off on a contract that allows a sponsor to stop an academic publication,” she wrote to Ms Kelly.

Months later, with the issue still apparently unresolved, Ms Robinson adopted a sterner tone. She noted in an email in March 2018 that, “Hopkins as an academic institution, and I as a faculty member therein, will not sign something that limits academic freedom in this manner,” nor “language that goes against current standards in systematic reviews and in guideline development”.

Not to reason XY

Eventually WPATH relented, and in May 2018 Ms Robinson signed a contract granting WPATH power to review and offer feedback on her team’s work, but not to meddle in any substantive way. After wpath leaders saw two manuscripts submitted for review in July 2020, however, the parties’ disagreements flared up again. In August the WPATH executive committee wrote to Ms Robinson that WPATH had “many concerns” about these papers, and that it was implementing a new policy in which WPATH would have authority to influence the EPC team’s output—including the power to nip papers in the bud on the basis of their conclusions.

Ms Robinson protested that the new policy did not reflect the contract she had signed and violated basic principles of unfettered scientific inquiry she had emphasised repeatedly in her dealings with WPATH . The Hopkins team published only one paper after WPATH implemented its new policy: a 2021 meta-analysis on the effects of hormone therapy on transgender people. Among the recently released court documents is a WPATH checklist confirming that an individual from WPATH was involved “in the design, drafting of the article and final approval of [that] article”. (The article itself explicitly claims the opposite.) Now, more than six years after signing the agreement, the EPC team does not appear to have published anything else, despite having provided WPATH with the material for six systematic reviews, according to the documents.

No one at WPATH or Johns Hopkins has responded to multiple inquiries, so there are still gaps in this timeline. But an email in October 2020 from WPATH figures, including its incoming president at the time, Walter Bouman, to the working group on guidelines, made clear what sort of science WPATH did (and did not) want published. Research must be “thoroughly scrutinised and reviewed to ensure that publication does not negatively affect the provision of transgender health care in the broadest sense,” it stated. Mr Bouman and one other coauthor of that email have been named to a World Health Organisation advisory board tasked with developing best practices for transgender medicine.

Another document recently unsealed shows that Rachel Levine, a transwoman who is assistant secretary for health, succeeded in pressing wpath to remove minimum ages for the treatment of children from its 2022 standards of care. Dr Levine’s office has not commented. Questions remain unanswered, but none of this helps WPATH ’s claim to be an organisation that bases its recommendations on science. ■

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